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CDC finds flu shots 42% effective this season, better than some recent years
This season’s influenza vaccines have been 42% effective so far, according to a new interim estimate from the Centers for Disease Control and Prevention, amounting to protection against the virus that appears as good or better than seasons going back to 2016.
First previewed Wednesday at a meeting of the CDC’s Advisory Committee on Immunization Practices, details of the latest vaccine effectiveness, referred to as VE, estimates were published Thursday in the agency’s Morbidity and Mortality Weekly Report.
“We’re right in the range that we typically see when the vaccine is a good match with the viruses that are circulating. Good VE, and it’s working consistent with past years,” said Sascha Ellington, head of the CDC’s influenza prevention and control team.
The exact strains selected to be targeted by flu vaccines are tweaked each year based on what health authorities project will be the best match to the circulating viruses each season. In recent years, vaccines have been designed to target four different subtypes of flu: two from the influenza A group of viruses and two from influenza B.
The estimates are from four ongoing studies backed by the agency which put together actively test patients and draw on records from immunization registries, clinics, urgent care services, emergency rooms, hospitals and health insurance claims around the U.S.
Estimates show vaccines this season were between 52% and 61% effective in protecting children against influenza hospitalization. In adults, the shots were estimated to be 41% to 44% effective.
While effectiveness looks good for this season, Ellington warned that declining vaccination rates means the U.S. could still see fewer hospitalizations and deaths prevented by vaccines this season.
“To prevent flu hospitalizations and deaths on the population level, we need both good vaccine effectiveness and we need people to get vaccinated,” she said.
Ellington said the agency continues to recommend that people get a flu vaccine if they have not yet this season. The CDC says significant flu activity can last until May.
Some regions of the country have reported renewed increases in flu activity for recent weeks, after a slowdown from a peak during the winter holidays.
High effectiveness for influenza B
Effectiveness looked especially high so far this season for influenza B infections, Ellington said.
This season marked the first since before 2020 with significant amounts of influenza B cases, after the COVID-19 pandemic upended the usual spread of the virus.
Based on data from outpatient settings, like urgent care clinics and emergency rooms, the vaccines were 78% effective in adults and at least 64% in kids for cutting the risk of a visit from influenza B.
“We really have to go back a number of years to look at influenza B effectiveness. And when you go back for those older years, you do see it ranging usually in the 40 to 60 percent range,” said Ellington.
Usual effectiveness for influenza A
Effectiveness estimates for influenza A, which typically makes up the lion’s share of cases, looked similar to previous years overall: from 46% to 59% in kids and 27% to 46% in adults for outpatient settings.
Overall, a majority of tests reported so far this season from public health labs have been from a subtype of influenza A known as A(H1N1)pdm09, the descendant of the swine flu virus that drove a flu pandemic in 2009. That is different from last year, when the influenza A(H3N2) virus dominated cases.
Ellington said that experts sometimes see vaccine effectiveness trend higher during seasons dominated by H1N1. But she cautioned that other factors, like changes to the virus and what strains were selected to be in the season’s shots, muddy the picture.
“I think the general consensus is that they would expect perhaps a little higher VE when it’s an H1N1 season, but that doesn’t always come to fruition,” she said.
Major change to the influenza vaccines coming
The new estimates come as the Food and Drug Administration is set to vote on the recipe used for next season’s influenza vaccines, at a meeting of its Vaccines and Related Biological Products Advisory Committee.
A major change could be in store. FDA and World Health Organization panels have called on flu manufacturers to strip out an obsolete component of the vaccines targeted at the influenza B Yamagata subtype, which disappeared during the COVID-19 pandemic.
That could effectively open up one of the seats in the vaccines, dropping them next season from quadrivalent formulations – targeting four different antigens in a single shot – to trivalent.
“As a result, it is likely that in the United States, all influenza vaccines in the 2024–2025 season will be trivalent,” wrote committee member Dr. Arnold Monto Wednesday, in an article published by the New England Journal of Medicine co-authored by officials from the FDA and the U.K. Health Security Agency.
Removing influenza B Yamagata could make room for new components in the flu vaccine recipe that might boost effectiveness, though these additions could be years away.
“Replacing the B/Yamagata component with another component or formulation will require further stepwise planning and is more of a long-term goal for improving vaccine effectiveness,” they wrote.
When Huntington Beach, Calif., detectives searched Rodney Alcala‘s Seattle storage locker during the murder investigation of 12-year-old Robin Samsoe in 1979, they discovered a cache of photos, many of them young women in suggestive, and even pornographic poses.
In March 2010, after a third jury in 30 years handed Alcala a death sentence, Huntington Beach police released more than 100 of those photos hoping to identify the women and some children, and learn if Alcala claimed still more victims.
Most of those who have been identified are alive and well.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
Unidentified women in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
Unidentified women in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified child in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified child in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
Unidentified women in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified child in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
Huntington Beach Police Dept.
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
Unidentified people in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified person in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified child in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
An unidentified woman in an image from Rodney Alcala’s photo cache.
Serial Killer’s Secret Photos
Unidentified women in an image from Rodney Alcala’s photo cache.
San Francisco Mayor London Breed conceded the mayoral race to Daniel Lurie Thursday afternoon with a social media post that congratulated her competitor.
The mayor also thanked the city and its residents for “the opportunity to serve the City that raised me” in the post on X just after 4:30 p.m. Thursday.
There had been rumblings that Breed might concede the race earlier Thursday having come in behind Lurie in the last vote count released Wednesday morning.
“Today, I called Daniel Lurie and congratulated him on his victory in this election,” the post read. “Over the coming weeks, my staff and I will work to ensure a smooth transition as he takes on the honor of serving as Mayor of San Francisco. I know we are both committed to improving this City we love.”
Breed spoke at a press conference less than an hour after the social media post to answer questions from reporters about her decision, reiterating some of what she said in her social media post.
“The city is on the rise. The office is bigger than just one person, and I called Daniel Lurie earlier today to congratulate him,” the mayor said. “And made it very clear my team and I stand ready to support him during his transition. We will always do everything we can to ensure the success of the city and that there is a smooth transition, so that the important work that has been done and needs to continue in San Francisco moves forward.”
When asked if this was the hardest speech she’d ever given, Breed quickly dismissed that idea.
“No, it’s not. There’s been other harder speeches. I mean I had to make a hard decision to close the city down during a global pandemic. I had to deal with…the racial reckoning that happened after the tragic death of George Floyd. I had to go out in the middle of the night and tell people that Mayor Ed Lee had passed away. There are numerous occasions.”
Six years ago, incumbent London Breed became the first Black woman to serve as mayor of San Francisco after the death of Mayor Ed Lee in late 2017. The then president of the San Francisco Board of Supervisors was automatically appointed as the city’s acting mayor early the morning after Lee’s death.
In June of 2018, Breed won the special election that was held to fill the office, defeating her main opponent, former state senator Mark Leno.
Breed faced a number of major challenges during her first term in office, including the COVID-19 pandemic, the city’s ongoing issues with drug abuse and homelessness, rising housing costs and a spike in retail crime that some chains cited as the reason behind closing stores in San Francisco.
While Breed has touted progress in reducing the number of homeless encampments and pushed programs to fill vacant business spaces downtown, the mayor’s struggles have led to 11 other candidates entering the race to challenge her for the job.
“Over the coming weeks, I plan to reflect on all the progress we’ve made. But today, I am proud that we have truly accomplished so much and my heart is filled with gratitude,” Breed’s message said in closing. “During my final two months as your Mayor, I will continue to lead this City as I have from Day One – as San Francisco’s biggest champion.”
Daniel Lurie has announced that he will speak to the media about the latest developments Friday morning.
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