Connect with us

CBS News

After she was given 24 hours to live, a rare transplant saved her life

Avatar

Published

on


At 24 years old, Danielle Perea was newly enrolled in a clinical lab science master’s program, living with her boyfriend in Louisiana, and generally enjoying her life — until one day, a stomachache led to her sitting in an area hospital, being told she had just hours left to live. 

Just a few days into her program, Perea woke with a “serious stomachache” that she first mistook for food poisoning, but when she used the bathroom she passed “frothy blood” that made her decide to go to the emergency room at a hospital she did not name because of pending litigation. Perea was told that a CT scan taken by doctors showed no signs of a problem. 

When her symptoms persisted, she went to another hospital where she was observed again, but still not diagnosed with anything. Doctors looked at the same CT scan, and said something like a clot was unlikely because of her age and relative health. On the third day of her symptoms, Perea began vomiting blood, and again returned to the emergency room as her symptoms intensified. 

An exploratory surgery revealed that there had been a blood clot in one of the vessels that carries blood from the small intestines, a condition called mesenteric ischemia. Surgeons attempted to salvage the organs, but found too much necrotic tissue. 

“They just saw that everything was completely black, necrotic, dead,” Perea told CBS News. “They (told my boyfriend) ‘There’s no way she’s going to survive this, you need to call her parents. Get anyone here who needs to be here, because she probably has 24 hours to live.'” 

screen-shot-2024-06-28-at-1-47-51-pm.png
Danielle Perea in hospice care before transplant.

Danielle Perea


Perea went into hospice care, but exceeded expectations, maintaining “strong vitals” for over a week. During that time, her mother and boyfriend searched for a miracle. They learned about Cleveland Clinic’s intestinal transplant program, the largest in the nation, and the head of the program, Dr. Kareem Abu-Elmagd, agreed to take Perea’s case. 

What is an intestinal transplant, and why are they so rare? 

An intestinal transplant replaces the small intestine with a new organ. Just 95 were conducted in the United States last year, according to Dr. Masato Fujiki, director of intestinal transplantation at Cleveland Clinic and one of the doctors who treated Perea. Eighteen of those were done at the Cleveland Clinic, making it the largest intestinal transplant program in the country. During the same time period, there were over 10,000 liver transplants and more than 4,000 heart transplants.

There are about 15,000 eligible organ donors each year, and there are not many patients eligible for an intestinal transplant. This allows doctors to “be very selective, to get the best organ,” Fujiki said. Ideal intestinal donors are people who are under the age of 50 and in good health, and who have stable blood pressure. 

While it’s not particularly difficult to find a suitable organ, intestinal transplants did not have a high success rate until recently, contributing to their rarity, Fujiki said. Intestines are a “difficult” organ to monitor, he said, and intestinal transplants have the highest rejection rate of any kind of organ transplant. 

The one-year graft survival rate for a patient who has an intestinal transplant was up to 82% in 2022, from a rate of 76.2% in 2018, according to national data. That’s still below the graft survival rate for more common procedures like liver transplants, which have a rate of 85 to 90%, Fujiki said. 


First-of-its-kind heart transplant in infant could possibly prevent organ rejection

04:21

An extended road to recovery 

Once Perea’s family learned about the intestinal transplant program and her case had been accepted at Cleveland Clinic, she was brought to the Ohio hospital. Her small bowel was almost entirely resected. Her condition was stabilized, and after several other procedures, she was officially added to the transplant list in the spring of 2019. 

Before the transplant, Perea spent a year and a half living on IV-administered nutrition because without the intestines, she couldn’t eat normally. The amount of time she spent being supported by machines meant Perea had to have another surgery to repair damage to her trachea before she could receive the transplant, extending the amount of time she had to wait. The coronavirus pandemic also complicated the process, forcing her to pass on an organ in April 2020. 

screen-shot-2024-06-28-at-1-48-43-pm.png
Danielle Perea ahead of her intestinal transplant.

Danielle Perea


Finally, in June 2020, Perea got the call she had been waiting for. 

“They were just like, ‘You need to get to the clinic right away.’ It wasn’t an option,” Perea said. 

The surgery took 10 hours, and even once the new organ was in place, Perea continued to spend time in the hospital, being readmitted for frequent fevers. In January 2021, she had another procedure to repair her abdominal wall and reverse her ileostomy, an incision made during the surgery. 

Now, four years after the operation, she told CBS News that she can live relatively normally, though she does take “about 40 pills a day.” There is the possibility she might need a kidney transplant in the future, because of the impact of anti-rejection medications on that organ, and she has annual appointments at the Cleveland Clinic to monitor the transplant, but everything has been “super normal” so far. 

“I don’t have any restrictions. My incisions healed well. I got married in November,” Perea said. “We bought a house. It’s just all going well.”

At Cleveland Clinic, she said, “they’re like, ‘Just keep living your life. There’s nothing stopping you.'” 

img-3302-original.jpg
Danielle Perea and her family after transplant.

Danielle Perea




Read the original article

Leave your vote

CBS News

7/2: CBS Evening News – CBS News

Avatar

Published

on


7/2: CBS Evening News – CBS News


Watch CBS News



Beryl leaves trail of destruction on Caribbean islands; Brooklyn organization tries to get more girls into skateboarding

Be the first to know

Get browser notifications for breaking news, live events, and exclusive reporting.




Read the original article

Leave your vote

Continue Reading

CBS News

Robert Towne, legendary Hollywood screenwriter of “Chinatown,” dies at 89

Avatar

Published

on


Robert Towne, the Oscar-winning screenplay writer of “Shampoo,” “The Last Detail” and other acclaimed films whose work on “Chinatown” became a model of the art form and helped define the jaded allure of his native Los Angeles, has died. He was 89.

Towne “passed away peacefully surrounded by his loving family” Monday at his home in Los Angeles, his publicist Carri McClure, told CBS News in a statement. She did not provide a cause of death.

In an industry which gave birth to rueful jokes about the writer’s status, Towne for a time held prestige comparable to the actors and directors he worked with. Through his friendships with two of the biggest stars of the 1960s and ’70s, Warren Beatty and Jack Nicholson, he wrote or co-wrote some of the signature films of an era when artists held an unusual level of creative control. The rare “auteur” among screen writers, Towne managed to bring a highly personal and influential vision of Los Angeles onto the screen.

Writer Robert Towne
Writer Robert Towne in audience during the 36th AFI Life Achievement Award tribute to Warren Beatty held at the Kodak Theatre on June 12, 2008 in Hollywood, California. 

Alberto E. Rodriguez/Getty Images for AFI


“It’s a city that’s so illusory,” Towne told The Associated Press in a 2006 interview. “It’s the westernmost west of America. It’s a sort of place of last resort. It’s a place where, in a word, people go to make their dreams come true. And they’re forever disappointed.”

Recognizable around Hollywood for his high forehead and full beard, Towne won an Academy Award for “Chinatown” and was nominated three other times, for “The Last Detail,” “Shampoo” and “Greystoke.” In 1997, he received a lifetime achievement award from the Writers Guild of America.

“His life, like the characters he created, was incisive, iconoclastic and entirely (original),” said “Shampoo” actor Lee Grant on X.

Towne was born Robert Bertram Schwartz in Los Angeles and moved to San Pedro after his father’s business, a dress shop, closed down because of the Great Depression. His father changed the family name to Towne.

Towne’s success came after a long stretch of working in television, including “The Man from U.N.C.L.E” and “The Lloyd Bridges Show,” and on low-budget movies for “B” producer Roger Corman. In a classic show business story, he owed his breakthrough in part to his psychiatrist, through whom he met Beatty, a fellow patient. As Beatty worked on “Bonnie and Clyde,” he brought in Towne for revisions of the Robert Benton-David Newman script and had him on the set while the movie was filmed in Texas.

Towne’s contributions were uncredited for “Bonnie and Clyde,” the landmark crime film released in 1967, and for years he was a favorite ghost writer. He helped out on “The Godfather,” “The Parallax View” and “Heaven Can Wait” among others and referred to himself as a “relief pitcher who could come in for an inning, not pitch the whole game.” But Towne was credited by name for Nicholson’s macho “The Last Detail” and Beatty’s sex comedy “Shampoo” and was immortalized by “Chinatown,” the 1974 thriller set during the Great Depression.

“Chinatown” was directed by Roman Polanski and starred Nicholson as J.J. “Jake” Gittes, a private detective asked to follow the husband of Evelyn Mulwray (played by Faye Dunaway). The husband is chief engineer of the Los Angeles Department of Water and Power and Gittes finds himself caught in a chaotic spiral of corruption and violence, embodied by Evelyn’s ruthless father, Noah Cross (John Huston).

Influenced by the fiction of Raymond Chandler, Towne resurrected the menace and mood of a classic Los Angeles film noir, but cast Gittes’ labyrinthine odyssey across a grander and more insidious portrait of Southern California. Clues accumulate into a timeless detective tale, and lead helplessly to tragedy, summed up by one of the most repeated lines in movie history, words of grim fatalism a devastated Gittes receives from his partner Lawrence Walsh (Joe Mantell): “Forget it, Jake, it’s Chinatown.”

The back story of “Chinatown” has itself become a kind of detective story, explored in producer Robert Evans’ memoir, “The Kid Stays in the Picture”; in Peter Biskind’s “East Riders, Raging Bulls,” a history of 1960s-1970s Hollywood, and in Sam Wasson’s “The Big Goodbye,” dedicated entirely to “Chinatown.” In “The Big Goodbye,” published in 2020, Wasson alleged that Towne was helped extensively by a ghost writer — former college roommate Edward Taylor. According to “The Big Goodbye,” for which Towne declined to be interviewed, Taylor did not ask for credit on the film because his “friendship with Robert” mattered more.

The studios assumed more power after the mid-1970s and Towne’s standing declined. His own efforts at directing, including “Personal Best” and “Tequila Sunrise,” had mixed results. “The Two Jakes,” the long-awaited sequel to “Chinatown,” was a commercial and critical disappointment when released in 1990 and led to a temporary estrangement between Towne and Nicholson.

Around the same time, he agreed to work on a movie far removed from the art-house aspirations of the ’70s, the Don Simpson-Jerry Bruckheimer production “Days of Thunder,” starring Tom Cruise as a race car driver and Robert Duvall as his crew chief. The 1990 movie was famously over budget and mostly panned, although its admirers include Quentin Tarantino and countless racing fans. And Towne’s script popularized an expression used by Duvall after Cruise complains another car slammed him: “He didn’t slam into you, he didn’t bump you, he didn’t nudge you. He rubbed you.

“And rubbin,′ son, is racin.'”

Towne later worked with Cruise on “The Firm” and the first two “Mission: Impossible” movies. His most recent film was “Ask the Dust,” a Los Angeles story he wrote and directed that came out in 2006. Towne was married twice, the second time to Luisa Gaule, and had two children. His brother, Roger Towne, also wrote screenplays, his credits include “The Natural.”



Read the original article

Leave your vote

Continue Reading

CBS News

Analyzing impact of Supreme Court’s Trump immunity decision

Avatar

Published

on


Analyzing impact of Supreme Court’s Trump immunity decision – CBS News


Watch CBS News



It’s been a day since the Supreme Court ruled that former President Donald Trump has immunity from criminal prosecution for official acts taken in office but that he is not protected from prosecution for unofficial acts. CBS News legal analyst Jessica Levinson joins to unpack the decision.

Be the first to know

Get browser notifications for breaking news, live events, and exclusive reporting.




Read the original article

Leave your vote

Continue Reading

Copyright © 2024 Breaking MN

Log In

Forgot password?

Forgot password?

Enter your account data and we will send you a link to reset your password.

Your password reset link appears to be invalid or expired.

Log in

Privacy Policy

Add to Collection

No Collections

Here you'll find all collections you've created before.