The Palestinian militant group Hamas said an Israeli airstrike Monday killed its leader in Lebanon.

Hamas said Fatah Sharif and his family were killed in the strike on the Al-Buss refugee camp in the southern port city of Tyre.

In the past week, Israel has frequently targeted Beirut’s southern suburbs, where Hezbollah has a strong presence – including a major strike on Friday that killed Hezbollah’s longtime leader, Hassan Nasrallah.

But on Monday, the first apparent Israeli airstrike on central Beirut in nearly a year of conflict leveled an apartment building.

It came after Israel hit targets across Lebanon in the past few days and killed dozens of people, with Hezbollah sustaining heavy blows to its command structure, including Nasrallah’s death.

Israeli officials had no immediate comment. 

The airstrike hit in central Beirut a multistory residential building, according to an Associated Press journalist at the scene. Videos showed ambulances and a crowd gathered near the building in a mainly Sunni district with a busy thoroughfare lined with shops.

The airstrike killed at least one person and wounded 16, an official with Lebanese Civil Defense said, speaking on condition of anonymity because he wasn’t authorized to speak to the media. He said the person killed was a member of the al-Jamaa al-Islamiya, or the Islamic Group, a Sunni political and militant group allied with Hezbollah.

A Palestinian leftist faction in Lebanon said three of its members were killed in the airstrike. The Popular Front for the Liberation of Palestine said in a statement early Monday that its military and security commanders in Lebanon and a third member were killed in the attack.

Neither militant group has played a significant role in the ongoing conflict between Israel and the Shiite militant group Hezbollah.

Earlier, Hezbollah confirmed that Nabil Kaouk, the deputy head of its Central Council, was killed Saturday, making him the seventh senior Hezbollah leader killed in Israeli strikes in a little over a week. They include the group’s founding members who had evaded death or detention for decades.

Hezbollah also confirmed that Ali Karaki, another senior commander, died in the strike that killed Nasrallah. Israel says at least 20 other Hezbollah militants were killed, including one in charge of Nasrallah’s security detail.

The Lebanese Health Ministry said at least 105 people were killed around the country in airstrikes Sunday. Two strikes near the southern city of Sidon, about 28 miles south of Beirut, killed at least 32 people, the ministry said. Separately, Israeli strikes in the northern province of Baalbek Hermel killed 21 people and wounded at least 47.

Lebanese media reported dozens of strikes in the central, eastern and western Bekaa and in the south, besides strikes on Beirut. Israel says it targets militants, but the strikes have hit buildings where civilians were living and the death toll was expected to rise.

In a video of a strike in Sidon, verified by the AP, a building swayed before collapsing as neighbors filmed it. One TV station called on viewers to pray for a family caught under the rubble, posting their pictures, as rescuers failed to reach them. The Lebanese Health Ministry reported at least 14 medics were killed over two days in the south.

President Biden said Sunday he would speak soon with Israeli Prime Minister Benjamin Netanyahu and believes an all-out war in the Middle East must be avoided. “It has to be,” Mr. Biden told reporters at Dover Air Force Base in Delaware as he boarded Air Force One to head to Washington.

Biden says Nasrallah’s death is a “measure of justice”

On Saturday, Mr. Biden said Nasrallah‘s death in the Israeli airstrike was a “measure of justice” for his many victims.

In a statement released by the White House, Mr. Biden said. “Nasrallah and the terrorist group he led, Hezbollah, were responsible for killing hundreds of Americans over a four-decade reign of terror,” including thousands of Israelis and Lebanese civilians.

White House national security spokesman John Kirby said Sunday that Israel’s airstrikes in Lebanon had “wiped out” Hezbollah’s command structure, but he warned the group will work quickly to rebuild it.

“I think people are safer without him walking around,” Kirby said of Nasrallah. “But they will try to recover. We’re watching to see what they do to try to fill this leadership vacuum. It’s going to be tough. … Much of their command structure has now been wiped out.”

Speaking on CNN’s “State of the Union,” Kirby sidestepped questions about whether the Biden administration agrees with how the Israelis are targeting Hezbollah leaders. The White House continues to call on Israel and Hezbollah to agree to a 21-day temporary cease-fire floated by the U.S., France and other countries during the U.N. General Assembly last week.

Meanwhile, wreckage from Friday’s strike that killed Nasrallah was still smoldering. Smoke rose over the rubble as people flocked to the site, some to check on what was left of their homes and others to pay respects, pray or simply to see the destruction.

In response to the dramatic escalation in Israeli strikes on Lebanon, Hezbollah significantly increased its rocket attacks in the past week, from several dozen to several hundred daily, the Israeli military said. The attacks injured several people and caused damage, but most of the rockets and drones were intercepted by Israel’s air defense systems or fell in open areas.

The army says its strikes have degraded Hezbollah’s capabilities and the number of launches would be much higher if Hezbollah hadn’t been hit.

Israel says it hit Houthi targets  

Also on Sunday, the Israeli military said dozens of its aircraft struck Houthi targets in Yemen in response to a recent attack. The military said it targeted power plants and sea port facilities in the city of Hodeida.

The Houthis launched a ballistic missile attack toward Israel’s Ben Gurion airport on Saturday when Netanyahu was arriving. The Houthi media office said the Israeli strikes hit the Hodeida and Rass Issa ports, along with two power plants in Hodeida city, a stronghold for the Iranian-backed rebels. The Houthi-run Health Ministry said the strikes killed four people and wounded 40 others.

The Houthis claimed they took precautionary measures ahead of the strikes, emptying oil stored in the ports, according to Nasruddin Ammer, deputy director of the Houthi media office. He said in a post on X that the strikes won’t stop the rebels’ attacks on shipping routes and on Israel.

A wave of Israeli airstrikes across large parts of Lebanon have killed more than 1,030 people – including 156 women and 87 children – in less than two weeks, according to Lebanon’s Health Ministry.

Hundreds of thousands of people have been driven from their homes. The government estimates around 250,000 are in shelters, with three to four times as many staying with friends or relatives, or camping out on the streets.

Hezbollah, a Lebanese militant group and political party backed by Iran, Israel’s chief regional rival, rose to regional prominence after fighting a devastating monthlong war with Israel in 2006 that ended in a draw.

Kaouk was a veteran member of Hezbollah going back to the 1980s and served as Hezbollah’s military commander in southern Lebanon during the 2006 war with Israel. The United States announced sanctions against him in 2020.

Hezbollah began firing rockets, missiles and drones into northern Israel after Hamas’ Oct. 7 attack out of Gaza triggered the war there. Hezbollah and Hamas are allies that consider themselves part of an Iran-backed “Axis of Resistance” against Israel.

The conflict has steadily ratcheted up to the brink of all-out war, raising fears of a region-wide conflagration.

Israel says it is determined to return some 60,000 of its citizens to communities in the north that were evacuated nearly a year ago. Hezbollah has said it will only halt its rocket fire if there is a cease-fire in Gaza, which has proven elusive despite months of indirect negotiations between Israel and Hamas led by the United States, Qatar and Egypt.