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Doctors perform first-ever combined heart pump and pig kidney transplant

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For the first time, surgeons at NYU Langone Health performed a combined mechanical heart pump and gene-edited pig kidney transplant, helping a 54-year-old woman with heart and kidney failure.

Before the two procedures, which took place earlier this month, New Jersey native Lisa Pisano faced heart failure and end-stage kidney disease that required routine dialysis, and she was not a candidate for a human transplant.

“I was pretty much done,” Pisano told CBS News chief medical correspondent Dr. Jon LaPook, who is also a professor at NYU Langone. “I couldn’t go up the stairs. I couldn’t drive. I couldn’t play with my grandkids. So when this opportunity came to me I was taking it.”

Now, she says, she’s feeling “great today compared to other days.” 

Dr. Robert Montgomery, NYU Langone Transplant Institute director, said she is currently “doing very well” in recovery. 

Pisano received only the second known transplant of a gene-edited pig kidney into a living person, and the first to include the pig’s thymus gland to aid against rejection, the hospital said. The transplant surgery took place on April 12, eight days after the heart pump, called a left ventricular assist device, or LVAD, was implanted on April 4.

Last month, surgeons at Massachusetts General Hospital in Boston transplanted a pig kidney into 62-year-old Rick Slayman, marking the first successful procedure of its kind in a living human patient in the world. 

Rejection issues with animal-to-human transplants, or xenotransplantation, have led to failures, largely due to people’s immune systems attacking the foreign tissue. Now, scientists are using genetic modification to better match those organs to humans.

“The human immune system rejects organs from animals, but Dr. Montgomery and his team used a pig kidney with one gene altered to make it more compatible,” LaPook explains.

Montgomery says this is about more than just the organ itself.

“This isn’t just about keeping somebody alive, it’s restoring them to their their lives,” he says. 

For Pisano, it means dreams of playing with her two young grandchildren for the first time in years, she says.

LaPook adds this procedure was done under the FDA’s “compassionate use” protocol. “So it’s not approved yet — but what an amazing technological tour de force,” he said. 



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Sen. Bob Menendez “put his power up for sale,” prosecutors say in closing arguments of bribery trial

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Sen. Bob Menendez federal bribery trial continues in Manhattan


Sen. Bob Menendez federal bribery trial continues in Manhattan

03:28

A prosecutor accused Sen. Bob Menendez in a closing argument at his bribery trial Monday of putting his power up for sale to benefit three New Jersey businessmen who allegedly bribed him with gold and cash.

The presentation by Assistant U.S. Attorney Paul Monteleoni, which will continue Tuesday, prompted the New Jersey Democrat to scoff as he left the courthouse, saying: “The government is intoxicated with their own rhetoric.”

Minutes earlier, Monteleoni urged the Manhattan federal court jury to follow a trail of hundreds of emails and text messages between the businessmen, Menendez and his wife to see the alleged link between the businessmen and stacks of cash, gold and a Mercedez-Benz convertible that investigators found in the couple’s home in June 2022. 

He said they’ll also be able to match fingerprint evidence linking the businessmen and Menendez to the bribes, including fingerprints on the tape that bound thousands of dollars in cash hidden in coat pockets, boots and boxes inside the Englewood Cliffs, New Jersey, home owned by his wife, Nadine Menendez.

Criminal Trial For US Senator Bob Menendez
Senator Robert Menendez, a Democrat from New Jersey, arrives at federal court in New York City on July 8, 2024.

Jeenah Moon/Bloomberg via Getty Images


Monteleoni said the senator “put his power up for sale.”

The prosecutor said it wasn’t enough that the senator was one of the most powerful people in Washington as the ranking member and later the chairman of the Senate Foreign Relations Committee, where he could block or approve hundreds of millions of dollars in military aid to nations such as Egypt.

“He also wanted to use it to pile up riches for himself and his wife,” Monteleoni said.

Monteleoni’s closing as the trial enters its ninth week in Manhattan federal court was about half finished when court concluded for the day.

As he left the courthouse, Menendez mocked the prosecutor’s closing, saying the government had “spent two hours on charts, not witnesses that came before the jury.” He added that Monteleoni had spent “two hours telling jurors about what they believe conversations should be that they never heard.”

Monteleoni said there was a clear pattern of corruption and told jurors to closely review communications between the senator, his wife and the businessmen to see evidence of bribes along with proof that they were trying to cover up their schemes.

Monteleoni said defense claims that gold in the house had mostly been inherited by Nadine Menendez was belied by serial numbers on gold bars which showed they had come from the businessmen who paid bribes.

“All this talk about Nadine having family gold is a distraction,” he said.

In return for bribes, prosecutors say, the senator took actions from 2018 to 2022 to protect or enhance the business interests of the businessmen — including pressuring a U.S. Department of Agriculture official to protect a halal certification monopoly Egypt granted to a New Jersey businessman, Wael Hana, and attempting to influence a federal prosecution of another New Jersey businessman, Fred Daibes. 

Senator Menendez Trial Continues In New York City
Wael Hana arrives for trial at Manhattan Federal Court on June 11, 2024, in New York City.

Michael M Santiago / Getty Images


Menendez, Hana and Daibes have pleaded not guilty and are on trial together. A third New Jersey businessman, Jose Uribe, pleaded guilty in the case and testified against the others during the federal trial, the second the senator has faced in the last decade. None of the defendants testified. 

An earlier trial against Menendez in New Jersey ended in 2017 with a deadlocked jury. After the charges were lodged last fall, Menendez was forced to give up his powerful chairmanship of the Senate Foreign Relations Committee.

Nadine Menendez is also charged in the case, but her trial has been postponed until August while she recovers from breast cancer surgery. She also has pleaded not guilty. 

As part of his defense, Menendez’s lawyers have argued that tens of thousands of dollars in cash found in the senator’s boots and jackets resulted from his habit of storing cash at home after hearing from his family how they escaped Cuba in 1951 with only the cash they had hidden in a grandfather clock. 

His lawyers have also asserted that Nadine Menendez, who began dating the senator in 2018 and married him two years later, kept him in the dark about her financial troubles and assistance she requested from the businessmen.

Menendez has held public office continuously since 1986, serving as a state legislator before serving 14 years as a U.S. congressman. In 2006, then-Gov. Jon Corzine appointed Menendez to the Senate seat he vacated when he became governor.

Several weeks ago, Menendez filed to run for reelection this year as an independent.



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Ukraine reeling after Russian missile strike on children’s hospital

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Ukraine reeling after Russian missile strike on children’s hospital – CBS News


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Ukraine is reeling after a Russian missile strike on a children’s hospital in the capital city of Kyiv. Nearly 40 civilians were killed and more than 170 injured in a barrage of missile strikes across Ukraine. Ramy Inocencio has disturbing images of the aftermath.

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“CBS Evening News” headlines for Monday, July 8, 2024

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“CBS Evening News” headlines for Monday, July 8, 2024 – CBS News


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Here’s a look at the top stories making headlines on the “CBS Evening News with Norah O’Donnell.”

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