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Meet some of the world’s cleanest pigs, raised to grow kidneys and hearts for humans

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Wide-eyed piglets rushing to check out the visitors to their unusual barn just might represent the future of organ transplantation – and there’s no rolling around in the mud here.

The first gene-edited pig organs ever transplanted into people came from animals born on this special research farm in the Blue Ridge mountains – behind locked gates, where entry requires washing down your vehicle, swapping your clothes for medical scrubs and stepping into tubs of disinfectant to clean your boots between each air-conditioned barn.

“These are precious animals,” said David Ayares of Revivicor Inc., who spent decades learning to clone pigs with just the right genetic changes to allow those first audacious experiments.

The biosecurity gets even tighter just a few miles away in Christiansburg, Virginia, where a new herd is being raised – pigs expected to supply organs for formal studies of animal-to-human transplantation as soon as next year.

Producing Pig Organs
Genetically modified piglets gather together at the Revivicor research farm near Blacksburg, Va., on May 29, 2024, where organs are retrieved for animal-to-human transplant experiments.

Shelby Lum / AP


This massive first-of-its-kind building bears no resemblance to a farm. It’s more like a pharmaceutical plant. And part of it is closed to all but certain carefully chosen employees who take a timed shower, don company-provided clothes and shoes, and then enter an enclave where piglets are growing up.

Behind that protective barrier are some of the world’s cleanest pigs. They breathe air and drink water that’s better filtered against contaminants than what’s required for people. Even their feed gets disinfected – all to prevent them from picking up any possible infections that might ultimately harm a transplant recipient.

Producing Pig Organs
A pig stands in a pen at the Revivicor research farm near Blacksburg, Va., on May 29, 2024, where organs are retrieved for animal-to-human transplant experiments.

Shelby Lum / AP


“We designed this facility to protect the pigs against contamination from the environment and from people,” said Matthew VonEsch of United Therapeutics, Revivicor’s parent company. “Every person that enters this building is a possible pathogen risk.”

The Associated Press got a peek at what it takes to clone and raise designer pigs for their organs – including a $75 million “designated pathogen-free facility” built to meet Food and Drug Administration safety standards for xenotransplantation.

Creating pigs to ease the shortage of human organs

Thousands of Americans each year die waiting for a transplant, and many experts acknowledge there never will be enough human donors to meet the need.

Animals offer the tantalizing promise of a ready-made supply. After decades of failed attempts, companies including Revivicor, eGenesis and Makana Therapeutics are engineering pigs to be more humanlike.

So far in the U.S., there have been four “compassionate use” transplants, last-ditch experiments into dying patients — two hearts and two kidneys. Revivicor provided both hearts and one of the kidneys. While the four patients died within a few months, they offered valuable lessons for researchers ready to try again in people who aren’t quite as sick.

Now the FDA is evaluating promising results from experiments in donated human bodies and awaiting results of additional studies of pig organs in baboons before deciding next steps.

Producing Pig Organs
In this photo provided by the United Therapeutics Corporation, a genetically modified pig stands inside the protective barrier at the company’s designated pathogen-free facility in Christiansburg, Va., in May 2024. These pigs will eventually supply organs for clinical trials. (United Therapeutics Corporation via AP)

Shelby Lum / AP


They’re semi-custom organs — “we’re growing these pigs to the size of the recipient,” Ayares noted — that won’t show the wear-and-tear of aging or chronic disease like most organs donated by people.

Transplant surgeons who’ve retrieved organs on Revivicor’s farm “go, ‘Oh my god that’s the most beautiful kidney I’ve ever seen,'” Ayares added. “Same thing when they get the heart, a pink healthy happy heart from a young animal.”

Producing Pig Organs
In this photo provided by the United Therapeutics Corporation, genetically modified pigs stand inside the protective barrier at the company’s designated pathogen-free facility in Christiansburg, Va., in May 2024. These pigs will eventually supply organs for clinical trials. (United Therapeutics Corporation via AP)

Shelby Lum / AP


The main challenges: how to avoid rejection and whether the animals might carry some unknown infection risk.

The process starts with modifying genes in pig skin cells in a lab. Revivicor initially deleted a gene that produces a sugar named alpha-gal, which triggers immediate destruction from the human immune system. Next came three-gene “knockouts,” to remove other immune-triggering red flags. Now the company is focusing on 10 gene edits — deleted pig genes and added human ones that together lessen the risk of rejection and blood clots plus limit organ size.

They clone pigs with those alterations, similar to how Dolly the sheep was created.

Twice a week, slaughterhouses ship Revivicor hundreds of eggs retrieved from sow ovaries. Working in the dark with the light-sensitive eggs, scientists peer through a microscope while suctioning out the maternal DNA. Then they slip in the genetic modifications.

“Tuck it in nice and smooth,” murmurs senior researcher Lori Sorrells, pushing to just the right spot without rupturing the egg. Mild electric shocks fuse in the new DNA and activate embryo growth.

Ayares, a molecular geneticist who heads Revivicor and helped create the world’s first cloned pigs in 2000, says the technique is “like playing two video games at the same time,” holding the egg in place with one hand and manipulating it with the other. The company’s first modified pig, the GalSafe single gene knockout, now is bred instead of cloned. If xenotransplantation eventually works, other pigs with the desired gene combinations would be, too.

Producing Pig Organs
David Ayares, president and chief scientific officer of Revivicor, looks at pigs at the company’s research farm near Blacksburg, Va., on May 29, 2024, where organs are retrieved for animal-to-human transplant experiments.

Shelby Lum / AP


Hours later, embryos are carried to the research farm in a handheld incubator and implanted into waiting sows.

Luxury accommodations for important pigs

On the research farm, Tom Petty’s “Free Fallin'” was serenading a piglet barn, where music acclimates the youngsters to human voices. In air-conditioned pens, the animals grunted excited greetings until it’s obvious their visitors brought no treats. The 3-week-olds darted back to the security of mom. Next door, older siblings laid down for a nap or checked out balls and other toys.

“It is luxury for a pig,” Ayares said. “But these are very valuable animals. They’re very smart animals. I’ve watched piglets play with balls together like soccer.”

About 300 pigs of different ages live on this farm, nestled in rolling hills, its exact location undisclosed for security reasons. Tags on their ears identify their genetics.

Producing Pig Organs
United Therapeutics’ designated pathogen-free facility in Christiansburg, Va., on May 29, 2024.

Shelby Lum / AP


“There are certain ones I say hi to,” said Suyapa Ball, Revivicor’s head of porcine technology and farm operations, as she rubbed one pig’s back. “You have to give them a good life. They’re giving their lives for us.”

A subset of pigs used for the most critical experiments – those early attempts with people and the FDA-required baboon studies – are housed in more restricted, even cleaner barns.

But in neighboring Christiansburg is the clearest signal that xenotransplantation is entering a new phase — the sheer size of United Therapeutics’ new pathogen-free facility. Inside the 77,000-square-foot building, the company expects to produce about 125 pig organs a year, likely enough to supply clinical trials.

Company video shows piglets running around behind the protective barrier, chewing on toys and nosing balls back and forth.

They were born in sort of a porcine birthing center connected to the facility, weaned a day or two later and moved into their super-clean pens to be hand-raised. In addition to the on-site shower, their caretakers must put on a new protective suit and mask before entering each suite of pig pens — another precaution against germs.

The pig zone is surrounded on all sides by security and mechanical systems that shield the animals. Outside air enters through multiple filtration systems. Giant vats hold backup supplies of drinking water. Standing over the pig rooms, VonEsch showed how pipes and vents were placed to allow maintenance and repair without any animal contact.

It will take years of clinical trials to prove whether xenotransplantation really could work. But if it succeeds, United Therapeutics’ plan is for even larger facilities, capable of producing up to 2,000 organs a year, in several places around the country.

The field is at a point where multiple kinds of studies “are telling us that there’s no train wrecks, that there’s no immediate rejection,” Ayares said. “The next two or three years are going to be super exciting.”



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Rare deluge floods parts of the Sahara desert for the first time in decades

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A rare deluge of rainfall left blue lagoons of water amid the palm trees and sand dunes of the Sahara desert, nourishing some of its driest regions with more water than they had seen in decades.

Southeastern Morocco‘s desert is among the most arid places in the world and rarely experiences rain in late summer.

The Moroccan government said two days of rainfall in September exceeded yearly averages in several areas that see less than 10 inches annually, including Tata, one of the areas hit hardest. In Tagounite, a village about 280 miles south of the capital, Rabat, more than 3.9 inches were recorded in a 24-hour period.

The storms left striking images of water gushing through the Saharan sands amid castles and desert flora. NASA satellites showed water rushing in to fill Lake Iriqui, a famous lake bed between Zagora and Tata that had been dry for 50 years.

Palm trees are reflected in a lake caused by heavy rainfall in the desert town of Merzouga, near Rachidia, southeastern Morocco, Oct. 2, 2024.
Palm trees are reflected in a lake caused by heavy rainfall in the desert town of Merzouga, near Rachidia, southeastern Morocco, Oct. 2, 2024.

AP Photo


According to NASA, such an occurrence is so rare in the region that a lake in Algeria, Sebkha el Melah, had only been filled six times from 2000-2021.

In desert communities frequented by tourists, 4x4s motored through the puddles and residents surveyed the scene in awe.

“It’s been 30 to 50 years since we’ve had this much rain in such a short space of time,” said Houssine Youabeb of Morocco’s General Directorate of Meteorology.

Such rains, which meteorologists are calling an extratropical storm, may change the course of the region’s weather in months and years to come as the air retains more moisture, causing more evaporation and drawing more storms, Youabeb said.

Palm trees are flooded in a lake caused by heavy rainfall in the desert town of Merzouga, near Rachidia, southeastern Morocco, Oct. 2, 2024.
Palm trees are flooded in a lake caused by heavy rainfall in the desert town of Merzouga, near Rachidia, southeastern Morocco, Oct. 2, 2024.

AP Photo


Six consecutive years of drought have posed challenges for much of Morocco, forcing farmers to leave fields fallow and cities and villages to ration water.

The bounty of rainfall will likely help refill the large groundwater aquifers beneath the desert that are relied upon to supply water in desert communities. The region’s dammed reservoirs reported refilling at record rates throughout September. However, it’s unclear how far September’s rains will go toward alleviating drought.

Water gushing through the sands and oases left more than 20 dead in Morocco and Algeria and damaged farmers’ harvests, forcing the government to allocate emergency relief funds, including in some areas affected by last year’s earthquake.



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Trail cameras capture the magical and violent world of Alaska’s wildlife

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Fat bear week gets off to controversial start


Fat bear week gets off to controversial start

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Millions of people worldwide tuned in for a remote Alaska national park’s “Fat Bear Week” celebration this month, as captivating livestream camera footage caught the chubby predators chomping on salmon and fattening up for the winter.

But in the vast state known for its abundant wildlife, the magical and sometimes violent world of wild animals can be found close to home.

Within half a mile of a well-populated neighborhood in Anchorage, the state’s biggest city, several trail cameras regularly capture animals ranging in size from wolverines to moose. And a Facebook group that features the animals caught on webcams has seen its number of followers grow nearly sixfold since September, when it posted footage of a wolf pack taking down a moose yearling.

This image made from video provided by Donna Gail Shaw shows a view from a trail camera of a brown bear and cub on July 18, 2024, in Anchorage, Alaska.
This image made from video provided by Donna Gail Shaw shows a view from a trail camera of a brown bear and cub on July 18, 2024, in Anchorage, Alaska.

Donna Gail Shaw via AP


But it’s not all doom-and-gloom videos on the page, and the actual death of the moose calf was not shown. The group, named Muldoon Area Trail Photos and Videos, also features light-hearted moments such as two brown bear cubs standing on their hind legs and enthusiastically rubbing their backs against either side of a tree to mark it.

Ten cameras capture lynx, wolves, foxes, coyotes, eagles, and black and brown bears — “just whatever is out here,” said Donna Gail Shaw, a co-administrator of the Facebook group.

In addition to the 290,000 or so human residents of Anchorage, nearly 350 black bears, 65 brown bears and 1,600 moose also call it home.

Joe Cantil, a retired tribal health worker, said the idea for the page started when looking down at the vast open lands of Alaska from an airplane on a hunting trip near Fairbanks.

“You’re out in the middle of nowhere, so you see animals acting however they act whenever we’re not around,” he said.

This image made from video provided by Donna Gail Shaw shows a view from a trail camera of wolves attacking moose on Sept. 12, 2024, in Anchorage, Alaska.
This image made from video provided by Donna Gail Shaw shows a view from a trail camera of wolves attacking moose on Sept. 12, 2024, in Anchorage, Alaska.

Donna Gail Shaw via AP


He later met wildlife officials in the Anchorage park conducting an inventory of predators. He saw them set up a trap and three webcams where a moose had been killed.

“When I saw that, I thought, ‘Yeah, I can do that,'” he said.

Cantil set up a low-tech camera and caught his first animal on it, a wolverine, fueling a passion that led to the creation of the Facebook page in 2017.

Then, while hiking, he met Shaw, a retired science education professor and associate dean of the College of Education at the University of Alaska Anchorage.

Shaw was intrigued by his game cameras and began bugging him to see the footage.

“Well, he finally got tired of me pestering him and one day he said, ‘You know, you can get your own camera,’ and so that started my hobby,” said Shaw, a native of Texas.

This image made from video provided by Donna Gail Shaw shows a view from a trail camera of a coyote on March 15, 2022, in Anchorage, Alaska.
This image made from video provided by Donna Gail Shaw shows a view from a trail camera of a coyote on March 15, 2022, in Anchorage, Alaska.

Donna Gail Shaw via AP


She started by strapping a single $60 camera to a tree. Now she has nine cameras, seven of which are active in Far North Bicentennial Park, a 4,000-acre park stretching for miles along the front range of the Chugach Mountains on the east side of Anchorage.

Her cameras are set up anywhere between a quarter-mile to a half-mile of the Chugach Foothills neighborhood and she frequently posts to the Facebook group page. Cantil also posts videos from his three cameras.

“I knew there was wildlife out here because I would occasionally run into a moose or a bear on the trail, but I didn’t know how much wildlife was out here until I put the cameras on it,” Shaw said.

She replaces batteries and storage cards about once a week, walking into the woods to do so armed with an air horn to announce her presence, two cans of bear spray and a .44-caliber handgun for protection.

This image made from video provided by Donna Gail Shaw shows a view from a trail camera of a brown bear and a black bear on Aug. 29, 2019, in Anchorage, Alaska.
This image made from video provided by Donna Gail Shaw shows a view from a trail camera of a brown bear and a black bear on Aug. 29, 2019, in Anchorage, Alaska.

Donna Gail Shaw via AP


Many of the page’s followers are Anchorage residents looking for information about which animals may currently be roaming around the popular trail system. Other users join to see what the cameras capture, including people from other states who “enjoy looking at the wildlife that we have here,” she said.

Shaw said that every few years, her cameras catch a wolf or two — and sometimes even a pack. This year she was surprised when a pack of five wolves came by, walking quietly in a single file.

Last month, while she collected memory cards, she saw moose fur on the ground across the creek from two of her cameras. After she spotted what looked like a roughed-up patch of dirt where a bear might bury its kill, she assumed it was another moose attacked by a black bear, similar to what happened earlier not too far away.

Donna Gail Shaw checks her trail camera on Sept. 26, 2024, near a populated neighborhood of Anchorage, Alaska.
Donna Gail Shaw checks her trail camera on Sept. 26, 2024, near a populated neighborhood of Anchorage, Alaska.

AP Photo/Mark Thiessen


But when she checked the memory card, it instead showed the wolves taking down the moose yearling as the moose’s mother attempted to protect her offspring by trying to kick the wolves away with her long legs.

Now, the demand for the page is growing, but Shaw said she’s done adding cameras.

“I think I’m at my camera max,” she said. “Nine is enough!”



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The investigation into Montana mom Jermain Charlo’s disappearance

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When Jermain Charlo‘s cellphone went silent in June 2018, her family suspected something was wrong. “She was very active on social media … she posted about everything,” Valenda Morigeau, Charlo’s aunt, told “48 Hours.” “So for her to not be active on social media, then I knew something was not right.” When Charlo didn’t respond to calls or texts, Morigeau, sick with worry, reported her missing to the Missoula Police Department. Six years later, Charlo still has not been found.

Jermain Charlo
Jermain Charlo

Valenda Morigeau


During that time, the Missoula Police Department and other agencies have been hard at work. What have investigators discovered about what may have happened to Charlo? And will she ever be found?

The story begins on the night Charlo was last seen.

June 15, 2018: Last night out at The Badlander bar

Jermain Charlo security camera video
Security footage shows Jermain Charlo, second from left, in the alley outside The Badlander on June 15, 2018. 

Missoula Police Department


On the night she disappeared, Jermain Charlo was at The Badlander bar in Missoula, Montana, around midnight. She’s captured in the alley behind the bar on security camera footage excerpt, shared exclusively with “48 Hours.” Charlo, second from left, is highlighted.

Detectives spoke to multiple people who were in the alley, including the man standing behind Charlo. He’s Michael DeFrance, Charlo’s ex-boyfriend and the father of her two children. Charlo and DeFrance had plans together that night, though it’s not clear why they met up or what they discussed.

June 15, 2018, just before midnight: Disappearing into the night

Jermain Charlo security camera video
Jermain Charlo and Michael DeFrance, highlighted, seen leaving The Badlander bar just before midnight on June 15, 2018.

Missoula Poilce Department


Just before midnight on June 15,  Charlo and DeFrance walked away in the alley behind The Badlander bar, as seen  in this screenshot from security footage.

Where did they go next? When investigators asked Michael DeFrance that question, he told them the same thing he told Charlo’s family when they asked: that he and Charlo had gotten into his truck and then he’d dropped her off at the Orange Street Food Farm, a supermarket about a five-minute drive from The Badlander.

In a subsequent police interview, however, DeFrance amended his story. He said that in fact he’d dropped Charlo off not at the Orange Street Food Farm itself, but in a residential area eight blocks west of the store. He said he dropped her off there because Charlo told him she was staying with a friend named “Cassidy” who lived nearby.

Detectives found the change in DeFrance’s stories interesting. They also were unable to find anyone in Charlo’s life named “Cassidy.” It turned out that Charlo didn’t really intend to stay at a friend’s place  that night, but at the apartment of her then-boyfriend Jacob, who lived in the area. Jacob was out of town but had told Charlo she could stay at his place.

Jermain’s family suspects that she did not want to tell DeFrance about her relationship with Jacob and may have lied to him about “Cassidy.” 

June 16, 2018, just before 1 a.m.: Jacob tries to call Jermain Charlo

Jermain Charlo
Jermain Charlo

Valenda Morigeau


Shortly before 1 a.m. that night, Charlo’s boyfriend Jacob attempted to call her cell. She never picked up the phone — instead, it rang several times before going to voicemail. Jacob told police he suspected that somebody purposely ended the call.

Though detectives never considered Jacob a suspect — he was out of the state that night — they did talk to him further to see what else he might know. He told them that the day before Charlo disappeared, she told him “that Michael had been yelling at her, asking if she was dating anyone and wanted to get back together with her.”

DeFrance has also never been named a suspect in Charlo’s disappearance.

June 17, 2018: Jermain Charlo reported missing

Jermain Charlo's aunt Valenda Morigeau
Valenda Morigeau, Jermain Charlo’s aunt.

CBS News


On June 17, 2018, Charlo’s mother reported her missing to the Tribal Police Department on the Flathead Reservation, but because Jermain went missing in Missoula, it would have to be reported to the Missoula Police Department.

Family called Missoula police but learned that the report had to be made at the station in person, not over the phone. So on June 20, 2018, Valenda Morigeau, Charlo’s aunt, made the drive to Missoula and spoke with an officer to file an official report.

Late June 2018: The community searches

Jermain Charlo search volunteers
One of many searches for Jermain Charlo.

KPAX


After Charlo disappeared, her family took matters into their own hands and contacted local organization The Lifeguard Group for help. Volunteers came out in support to search for Charlo. This was just the first of many searches the community would hold over the months and years to come.

“We’ve told the family that we’re not going to stop no matter what. And we will search for Jermain as if she’s alive, until we find her,” said Lowell Hochhalter, president and co-founder of The Lifeguard Group.

June 26, 2018: The lead detective 

Detective Guy Baker
Detective Guy Baker of the Missoula Police Department.

CBS News


The Missoula Police Department’s investigation began the day Morigeau reported her niece missing. However, the first detective assigned only worked the case briefly before he had scheduled time off. It wasn’t until June 26, 10 days after Charlo disappeared, that Det. Guy Baker was assigned to the case. He would doggedly lead the investigation for the next six years, determined to find Charlo.

“I’m very much committed to finding her,” Baker told “48 Hours.” “I wanna bring justice to Jermain and hold accountable who’s responsible.”

June 27, 2018: The cellphone data

The Evaro Hill cell tower
The Evaro Hill cell tower.

CBS News


On June 27, 2018, detectives obtained data linked to Charlo’s cellphone. The data indicated that between the hours of 2 a.m. and 10 a.m. in the early morning hours of June 16, 2018, after she disappeared, Charlo’s cell was pinging off a cell tower in the area known as Evaro Hill.

Evaro Hill is a rugged, heavily forested area north of Missoula, and it’s where DeFrance, Charlo’s ex-boyfriend, was living at the time. DeFrance told investigators that he’d dropped Charlo off in Missoula around 1 a.m. So, why was her phone pinging north of the city hours later? DeFrance changed his story and told investigators that Charlo’s phone was with him.

Missoula County Deputy Attorney Brittany Williams told “48 Hours,” “In a subsequent interview, [DeFrance] provided a statement that she left her cellphone and he attempted to go through her cellphone and he was unable to get into her cellphone.”

Then DeFrance told authorities that two days later on June 18 — while Charlo’s family was desperately calling law enforcement for help — he discarded Charlo’s phone in Idaho at mile marker 94 on Highway 12. Law enforcement searched the area but never found the phone.

“The phone’s never been recovered,” confirms Baker. Charlo’s family wonders why DeFrance would throw Jermain’s phone away. Baker declined to comment on a possible motive for disposing of the phone. “48 Hours” requested an interview with DeFrance through his attorney. He declined our request. 

June 27, 2018: Michael DeFrance’s mother speaks to police

On the same day that the cellphone data was obtained, officers from the Missoula County Sheriff’s Office went to DeFrance’s property and spoke with his mother Jennifer DeFrance. According to police documents, Jennifer DeFrance told an officer that Charlo had never been to the residence. She also reported that “Michael was still in love with Jermain and wanted to get back together with her.”

Summer 2018: “Swept away in an instant”

Interstate 90 running through Montana
Interstate 90 running through Montana.

CBS News


Over the remainder of the summer, detectives investigated the idea that Charlo may have been a victim of human trafficking.

“We had some information early on that there might have been some people in Missoula from out of state that were trying to buy a girl,”  Baker told “48 Hours.” “And I was thinking there was a connection there.”

Williams described the trafficking situation in the state. “I think people have an idea that Montana is rural and undeveloped, and we don’t have major crimes that occur here,” she said. “But the fact of the matter is, we have one of the largest interstates that runs through our state right here through Missoula, Montana … there are people who can be swept away in an instant.”

Eventually, investigators were able to rule out the idea that Charlo was a victim of human trafficking. Williams told “48 Hours” in 2024, “I think that we have enough evidence through this investigation that lends itself to believe something else has happened to her.”

August 2, 2018: A warrant for Michael DeFrance’s property

An officer with the Missoula County Sheriff’s Department filed a search warrant application on August 2, 2018, that stated the officer had reason to believe that a crime had been committed in Missoula.

The application asked a judge to approve a search of DeFrance’s property on Evaro Hill. The officer hoped to “visually observe and simultaneously video record by ground or air, at any time of the day or night, the outside of the premises including all grounds.” It also asked for thermal imaging of the property.

Documents show that the search warrant application was approved by a judge, but officers declined to comment on the results of any of their searches of the DeFrance property. They do confirm that Charlo has not been found, and Michael DeFrance has never been named a suspect or charged with anything in relation to her disappearance.

Oct. 2, 2018: Firearms seized

ns seized from Michael DeFrance's property.
Guns seized from Michael DeFrance’s property.

District Court of Montana


In October 2018, police conducted another search of DeFrance’s Evaro Hill property. At this point, Charlo had been missing for more than three months.

On the property officers found and seized guns including the ones pictured. DeFrance had a prior conviction that prohibited him from owning firearms. In May 2013, DeFrance had pleaded guilty to a misdemeanor charge of Partner or Family Member Assault against Charlo, his then-girlfriend. When DeFrance was sentenced for this incident, part of his sentence was a loss of his firearm rights.

According to a 2013 police report, DeFrance admitted to hitting Charlo with an open hand, then twice more with his fist. Charlo reported that DeFrance had shoved her onto the hood of his van, punched her in the ear, the temple, and the cheekbone, and then spit in her face and told her she was horrible.

In October 2018 Baker asked DeFrance if he was aware he wasn’t supposed to have firearms because of his previous conviction. According to court documents, DeFrance replied, “I was never clear on that.”

2019-2021: The trail goes cold

Jermain Charlo billboard
On Highway 93, en route to Missoula, it’s hard to miss this billboard and Jermain Charlo’s haunting gaze. 

CBS News


In October 2018, Charlo’s family and the Confederated Salish and Kootenai Tribes put her information on a billboard. They hoped that someone would drive by and recognize Jermain. For six years, her gaze has haunted drivers as they travel down that road.

Baker wouldn’t tell “48 Hours” much about his investigation, as it is ongoing and many of the documents are sealed. But he insists the case never truly went cold. He has been consistently searching for Charlo over the years, and the investigation has never stopped. He is committed to finding Jermain.

“I guess when I see that billboard, I’m frustrated,” he said. “I’ve never worked a case like this before. We’ve tried to uncover and turn over every rock possible.”

July 28, 2021: Michael DeFrance arrested on firearms possession charges

In July 2021, Michael DeFrance was arrested for possession of the firearms police had confiscated in 2018. The case was investigated by the FBI. In October 2021, an indictment charged DeFrance with one count of prohibited person in possession of firearms and ammunition, and three counts of false statement during a firearms transaction. 

April 26, 2023: Michael DeFrance goes on trial for firearms violations

DeFrance was found guilty of all four counts of firearms-related violations after his two-day trial in federal court. Charlo’s mother and her aunt Valenda Morigeau both testified to the nature of Charlo and DeFrance’s relationship around the time of the 2013 partner or family member assault conviction, and Baker spoke about finding the guns at DeFrance’s residence.

DeFrance was sentenced in September 2023 to 21 months in prison and was given a lifetime ban on firearms and ammunition. On the same day, DeFrance filed an appeal. He has not served any time pending that appeal.

Today: hoping for justice

Valenda Morigeau
Jermain’s aunt Valenda Morigeau standing for justice.

Jen Murphy


Jermain Charlo’s family still hopes that one day she might be found, though they no longer believe she is alive. For Charlo’s aunt Dani Matt, justice for Charlo means “bringing her home, and letting her rest with our family up on the hill.”

“I will never stop looking for her,” said Morigeau. “I’ve met so many families that have had a loved one disappear. And I want other families to know that, like, it’s OK to keep pushing and it’s OK to keep their name out there. We have to fight for justice for our loved ones.” 



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